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Keywords: antibiotic
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Biochem Soc Trans (2019) 47 (2): 671–677.
Published: 08 March 2019
...Anna Lankester; Shafayeth Ahmed; Lisa E. Lamberte; Rachel A. Kettles; David C. Grainger In Escherichia coli , the marRAB operon is a determinant for antibiotic resistance. Such phenotypes require the encoded transcription factor MarA that activates efflux pump expression. To better understand all...
Includes: Supplementary data
Biochem Soc Trans (2014) 42 (4): 1052–1055.
Published: 11 August 2014
... pantothenamides (pantetheine analogues with antibiotic activity) against breakdown by plasma VNN, thereby preserving their antibiotic activity. Combination of pantothenamides with a VNN inhibitor showed a strong activity against Staphylococcus aureus and Staphylococcus pneumoniae when assayed in the presence...
Biochem Soc Trans (2013) 41 (6): 1355–1364.
Published: 20 November 2013
...Mervyn J. Bibb Actinomycetes are prolific producers of natural products with a wide range of biological activities. Many of the compounds that they make (and derivatives thereof) are used extensively in medicine, most notably as clinically important antibiotics, and in agriculture. Moreover...
Biochem Soc Trans (2012) 40 (6): 1438–1442.
Published: 21 November 2012
...Margaret A. Riley; Sandra M. Robinson; Christopher M. Roy; Morgan Dennis; Vivian Liu; Robert L. Dorit Pathogenic bacteria resistant to many or all antibiotics already exist. With the decline in microbiological research at pharmaceutical companies, the high rate at which resistance has evolved...
Biochem Soc Trans (2008) 36 (4): 567–574.
Published: 22 July 2008
... our laboratory to this worldwide effort. These include the determination of the structure of the 30S ribosomal subunit and its complexes with antibiotics, the role of the 30S subunit in decoding, and the high-resolution structure of the entire 70S ribosome complexed with mRNA and tRNA. Ribosomes...
Biochem Soc Trans (2003) 31 (3): 487–492.
Published: 01 June 2003
...C.T. Walsh; H.C. Losey; C.L. Freel Meyers In the biosynthesis of several classes of antibiotics, sugars are attached to aglycone scaffolds by antibiotic-specific glycosyltransferases in the latter stages of the pathways. Two glycosylation pathways will be examined: the glycopeptide antibiotics...