..., or (iii) induce SOS response that generally affects DNA repair and antibiotic resistance. These hypotheses should guide future investigations of the involvement of pAgos in the emergence of resistance to ciprofloxacin and, possibly, other antibiotics. Correspondence: Andrey Kulbachinskiy ( avkulb...

... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . adaptation antibiotic resistance host-pathogen interaction peptidoglycan Figure 1. Chemical structure of peptidoglycan with enzymatic cleavage sites...

... ) 30 4 2024 3 6 2024 4 6 2024 © 2024 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2024 antibiotic hyper-resistance antibiotic resistance isoleucyl-tRNA synthetase mupirocin protein synthesis Mupirocin (pseudomonic acid...

...Callaghan Cylke; Fangwei Si; Shiladitya Banerjee Characterizing the physiological response of bacterial cells to antibiotic treatment is crucial for the design of antibacterial therapies and for understanding the mechanisms of antibiotic resistance. While the effects of antibiotics are commonly...

... predominantly affects a subpopulation of cells that experience delayed adaptation to the stress ( Figure 2B ). Considering that infection of macrophages is associated with DNA alkylation stress [ 99 ], such an effect may also contribute to the dynamics of mutagenesis inside a host. antibiotic resistance...

... of neighbouring promoters. We suggest that many bacterial promoters might be susceptible to similar position-dependent effects and we review recent data showing that the expression of mobile genes encoding antibiotic-resistance determinants is also location-dependent, both when carried on a bacterial chromosome...

...Ciara Tyrrell; Catherine M. Burgess; Fiona P. Brennan; Fiona Walsh Antibiotic resistance is currently one of the greatest threats to human health. The global overuse of antibiotics in human medicine and in agriculture has resulted in the proliferation and dissemination of a multitude of antibiotic...

... variances of the two drugs. Zhang et al. prepared a hybrid of RIF-SV and GE23077 which exhibited activity against WT and resistant RNAPs [ 58 ]. antibiotic resistance antibiotics mechanism of action of antibiotics rifampicin RNA polymerase transcription Antibiotic resistant infections...

... Pseudomonas aeruginosa and Escherichia coli . Our current work on colicin-like bacteriocins aims to determine whether these potent antimicrobial agents are effective at killing bacteria growing in the biofilm state and during infection. Antibiotic resistance is recognized as a major health concern and can...

... to host and antibiotic selection pressure, and this is achieved by point mutations. Almost all antibiotic resistance emerges in this way, and data from clinical and in vitro studies indicate that M. tuberculosis exists with pre-existent mutants that remain as a small proportion of the population because...

... ). Enzyme Mechanism – A Structural Perspective, a Biochemical Society Focused Meeting held at St. Andrews University, 12–14 January 2003 16 December 2002 © 2003 Biochemical Society 2003 acetyltransferase aminoglycoside antibiotic resistance Mycobacterium tuberculosis Salmonella...