... and regulation could be achieved by similar mechanisms. In the present review, we describe the molecular properties of crenarchaeal chromatin proteins and discuss the possible role of these architectural proteins in organizing the crenarchaeal chromatin and in gene regulation. 1 To whom correspondence...

... the helical repeat, helix melting and/or flexibility, resulting in DNA stabilization. Figure 1 Mechanisms of positive supercoiling Top: right-handed DNA wrapping by an architectural protein is a non-covalent conformational modification reversible upon protein release. However, in a topologically...

...Rosalie P.C. Driessen; Remus Th. Dame Architectural proteins play an important role in compacting and organizing the chromosomal DNA in all three kingdoms of life (Eukarya, Bacteria and Archaea). These proteins are generally not conserved at the amino acid sequence level, but the mechanisms...

...Remus Th. Dame Architectural proteins play a key role in the folding, organization and compaction of genomic DNA in all organisms. By bending, bridging or wrapping DNA, these proteins ensure that its effective volume is reduced sufficiently to fit inside the cell or a dedicated cellular organelle...