..., some asymmetric structures exist, and asymmetry also often forms transiently, intractable to traditional structure determination methods. Here, we explore the role of protein complex symmetry and asymmetry in cellular signalling, focusing on receptors, transcription factors and transmembrane channels...

... Licence 4.0 (CC BY) . ABC transporter acyl-CoA asymmetry mechanism β-oxidation peroxisome thioesterase A distinctive function of peroxisomes is the β-oxidation pathway in which fatty acids (FA) are degraded with the concomitant generation of acetyl-CoA [ 1 ]. Genetic and biochemical...

... conformation. Note the domain swapping where TMD2 (yellow) contacts NBD1 (blue) and TMD1 (green) contacts NBD2 (purple). ATP-binding cassette (ABC) transporter acyl-CoA asymmetry β-oxidation peroxisome thioesterase Figure 2 Proposed transport mechanism for CTS Fatty acids are released...