... discovered in the last five years. A bioinformatics perspective is held here, hence sequence and structure comparison overview is presented, and also a comparison of genomic neighbourhoods of the families. We perform a phylum-level census of the families. Also, we discuss apparent pseudokinases that turned...

[email protected] ) . 14 4 2015 © 2015 Authors; published by Portland Press Limited 2015 bioinformatics protein structure proteome scoring function tandem repeats Next-generation sequencing platforms are revolutionizing life sciences, medicine and agriculture. A huge number of newly...

... identified as a serendipitous discovery. Hence, characterization of moonlighting proteins using bioinformatics approaches can have a significant impact on the overall understanding of protein function. In this work, we provide a short review of existing computational approaches for illuminating...

... if bioinformatics could predict protein multifunctionality, especially because of the large amounts of sequences coming from genome projects. In the present article, we describe several approaches that use sequences, structures, interactomics and current bioinformatics algorithms and programs to try to overcome...

... in a rich source of novel glycan structures and new possibilities for glycoprospecting and glycoengineering. However, assigning genetic information in predicted glycan biosynthetic pathways to the overall structural information is complex. Bioinformatic analysis is required, linked to systematic mutagenesis...

... ). 30 10 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 ATPase associated with various cellular activities (AAA) bioinformatics protein biochemistry Sulfolobus solfataricus Vps4 homologue AAA (ATPase associated with various cellular activities...

..., on a large scale, where operative bioinformatic skills are not necessary to access the results. Each of these has a different emphasis on methodology and utility, e.g. the provision of protease and inhibitor alignments in MEROPS, but TreeFam ( http://www.treefam.org/ ) is specifically described here...

... rather than a cause of the disease process. Bioinformatics can help sift the terabytes of data in public and proprietary databases and extrapolate protein function to identify the most plausible candidates [ 5 ]. Nevertheless, considerable experimental data may still be required to fully validate...

.... Biochemical analysis has identified both general and specific mRNA-binding proteins as components of the regulation of chloroplast translation, and has revealed that chloroplast translation is related to bacterial translation but is more complex. Utilizing proteomic and bioinformatic analyses, we have...

... cycle control, apoptosis, gene regulation and metastasis. As the number of these biological targets increases, reliance on bioinformatics and chemoinformatics to improve decision making, by identifying characteristics of successful drugs and sharing knowledge gained within the scientific community, has...