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Keywords: bone morphogenetic protein (BMP) signalling
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Articles

Emerging roles of the bone morphogenetic protein pathway in cancer: potential therapeutic target for kinase inhibition

Pawina Jiramongkolchai, Philip Owens, Charles C. Hong
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (4): 1117–1134.
https://doi.org/10.1042/BST20160069
Published: 15 August 2016
... cancer cell lines in a dose-dependent manner, an effect that can be completely inhibited by the BMP2 antagonist, Noggin [ 62 ]. Furthermore, BMP2 increased tumour growth [ 62 ] and enhanced tumour angiogenesis in murine lung cancer models [ 63 ]. bone morphogenetic protein (BMP) signalling...
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Articles

The role of chordin fragments generated by partial tolloid cleavage in regulating BMP activity

Helen Troilo, Anne L. Barrett, Alexander P. Wohl, Thomas A. Jowitt, Richard F. Collins, Christopher P. Bayley, Alexandra V. Zuk, Gerhard Sengle, Clair Baldock
Journal: Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (5): 795–800.
https://doi.org/10.1042/BST20150071
Published: 09 October 2015
.... Liu N. Kang J. Bone morphogenetic protein (BMP) signaling regulates mitotic checkpoint protein levels in human breast cancer cells Cell Signal. 2012 24 961 968 10.1016/j.cellsig.2011.12.019 22234345 4 Wang J. Guo J. Liu J. Wei L. Wu G. BMP-functionalised...
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Includes: Supplementary data