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Keywords: calcitonin-receptor-like receptor (CRLR)
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2002) 30 (4): 460–464.
Published: 01 August 2002
... other proteins to constitute a functional CGRP receptor: calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein 1 (RAMP1).CRLR has the stereotypical seven-transmembrane topology of a G-protein-coupled receptor; it requires RAMP1 for trafficking to the cell surface...
Articles
D. M. Smith, H. A. Coppock, D. J. Withers, A. A. Owji, D. L. Hay, T. P. Choksi, P. Chakravarty, S. Legon, D. R. Poyne
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2002) 30 (4): 432–437.
Published: 01 August 2002
... biological actions are mediated via CGRP type 1 (CGRP 1 ) receptors and by specific adrenomedullin receptors. Although the pharmacology of these receptors is distinct, they are both represented in molecular terms by the type II family G-protein-coupled receptor, calcitonin-receptor-like receptor (CRLR...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2002) 30 (4): 451–455.
Published: 01 August 2002
...A. C. Conner; D. L. Hay; S. G. Howitt; K. Kilk; Ü. Langel; M. Wheatley; D. M. Smith; D. R. Poyner The receptor for calcitonin-gene-related peptide (CGRP) is a heterodimer formed by calcitonin-receptor-like receptor (CRLR), a type II (family B) G-protein-coupled receptor, and receptor-activity...