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Keywords: calmodulin
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Biochem Soc Trans (2012) 40 (4): 653–655.
Published: 20 July 2012
... for the spreading of tau pathology in these neurodegenerative disorders. 1 To whom correspondence should be addressed (email javila@cbm.uam.es ). 12 1 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 calmodulin extracellular tau tau secretion ventral dentate...
Biochem Soc Trans (2011) 39 (2): 694–699.
Published: 22 March 2011
...–cell adhesion, cytokinesis and apoptosis. These processes rely on protein–protein interactions, and understanding these (and how they influence one another) is critical in determining how the IQGAPs function. A key group of interactions is with calmodulin and the structurally related proteins myosin...
Biochem Soc Trans (2007) 35 (5): 919–922.
Published: 25 October 2007
... versatility among PMCA isoforms, with specific pumps being essential for cochlear hair cell function, sperm motility, feedback signalling in the heart and pre- and post-synaptic Ca 2+ regulation in neurons. The functional versatility of PMCAs is due to differences in their regulation by CaM (calmodulin...
Biochem Soc Trans (2006) 34 (4): 480–483.
Published: 21 July 2006
..., can sequester calmodulin for its own regulatory purposes. These devices are a sampling of the multiple layers of organization that are in place – even in a simple cell – to ensure faithful and economical communication of the cAMP message. 1 To whom correspondence should be addressed (email...
Biochem Soc Trans (2006) 34 (3): 381–384.
Published: 22 May 2006
... The Biochemical Society 2006 acetylcholine calcium signalling calcium-binding protein calmodulin mitochondrion pancreatic acinar cell Local calcium transients ( Figure 1 A) are the main form of calcium signalling in pancreatic acinar cells. These transients preferentially occur in the part...
Biochem Soc Trans (2005) 33 (6): 1319–1322.
Published: 26 October 2005
... interference ablation of defined AKAPs. 1 email dmfc2@cam.ac.uk 30 6 2005 © 2005 The Biochemical Society 2005 adenylate cyclase A-kinase anchoring protein (AKAP) calmodulin capacitative Ca 2+ entry (CCE) cyclic nucleotide-gated channel (CNG channel) lipid raft Membrane...
Biochem Soc Trans (2004) 32 (5): 868–870.
Published: 26 October 2004
... and 3) and group III (4, 6–8) mGluRs. In the present study, we used a Y2H (yeast two hybrid) screen to identify proteins that interact with the C-terminal intracellular tail of mGluR3. Prominent among the candidate receptor interacting proteins was calmodulin, a Ca 2+ sensor known to bind identifiable...
Biochem Soc Trans (2003) 31 (5): 912–915.
Published: 01 October 2003
... April 2003 © 2003 Biochemical Society 2003 adenylate cyclase calmodulin calcium cAMP-dependent protein kinase caveolae phosphodiesterase Abbreviations used: AC1, AC2, AC3, etc., adenylate cyclase types 1, 2, 3, etc; CCE, capacitative Ca 2+ entry; [Ca 2+ ] i , intracellular...
Biochem Soc Trans (2003) 31 (3): 502–505.
Published: 01 June 2003
... binding of calmodulin (CaM) at elevated intracellular Ca 2+ levels to produce NO as part of a number of cell signalling pathways. CaM binds to the linker region between the two domains and activates the enzyme by inducing intramolecular electron transfer. Protein-engineering experiments have shown...