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Keywords: carboxy-anhydrase IX
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Articles
Treatment of metastatic renal cell carcinoma (mRCC) with CAIX CAR-engineered T-cells–a completed study overview
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (3): 951–959.
Published: 09 June 2016
... of carboxy-anhydrase-IX (CAIX). Twelve patients with CAIX+ mRCC were treated in three cohorts with a maximum of 10 daily infusions of 2×10 7 to 2×10 9 CAR T-cells. Circulating CAR T-cells were transiently detectable in all patients and maintained antigen-specific immune functions following their isolation...
