... the physiological implications of this crosstalk and identify gaps in our knowledge that will improve our understanding of cellular mechanosensing. cell adhesion ion channels mechanotransduction PIEZO channels Cells utilize an elaborate mechanosensing program to gauge the physical properties...

... cadherins in collective cell migration, specifically focusing on four in vivo model systems in development: the Drosophila border cells, zebrafish mesendodermal cells, Drosophila follicle rotation, and Xenopus neural crest cells. cadherins cell adhesion collective cell migration Cell migration...

...Claudia Owczarek; Yassmin Elmasry; Maddy Parsons Coxsackievirus and adenovirus receptor (CAR) is a transmembrane cell–cell adhesion receptor that forms homodimers across junctions and plays a key role in mediating epithelial barrier integrity. CAR can also heterodimerise with receptors...

... suggest several areas for more in-depth and interdisciplinary hypothesis testing. 3 12 2022 10 4 2023 18 4 2023 © 2023 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2023 c1q/TNF superfamily C1Ql cell adhesion cell signaling...

...Giulia Mana; Donatella Valdembri; Guido Serini Spatiotemporal control of integrin-mediated cell adhesion to the extracellular matrix (ECM) is critical for physiological and pathological events in multicellular organisms, such as embryonic development, angiogenesis, platelet aggregation, leukocytes...

...Lilian Schimmel; Emma Gordon Endothelial cell–cell adhesion within the wall of the vasculature controls a range of physiological processes, such as growth, integrity and barrier function. The adhesive properties of endothelial cells are tightly controlled by a complex cascade of signals transmitted...

... work into the function of APPL1 in cell migration and adhesion. Correspondence: Donna J. Webb ( [email protected] ) 15 12 2016 17 3 2017 22 3 2017 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 cell adhesion...

.... bacterial adhesion cell adhesion host–microbe interactions microbiology Bacteria have evolved an abundance of mechanisms to engage with host cells, and manipulate their cellular signaling programmes to facilitate colonization. Most, if not all of these, strictly depend on bacterial adhesion...

... summarize the current knowledge on kinesin functions in cell migration. 1 To whom correspondence should be addressed (email [email protected] ) . 16 10 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 cell adhesion cell migration force generation...

... and functional characterization of ILK and the long-standing debate regarding its reported kinase activity. 1 To whom correspondence should be addressed (email [email protected] ). 23 4 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 actin cell adhesion...

... that was secreted by fetal urogenital sinus mesenchymal cells. Purified ps20 exhibited several activities that centre on cell adhesion, migration and proliferation. The WFDC1 gene was cloned, contained seven exons, and was mapped to chromosome 16q24, suggesting that it may function as a tumour suppressor; however...

... as associated with certain types of cancer. However, the mechanistic role of this form of glycosylation in many of these instances is unclear. Here we describe how one glycosyltransferase responsible for initiating mucin-type O-glycosylation (PGANT3), specifically modulates integrin-mediated cell adhesion...

... compilation © 2010 Biochemical Society 2010 assembly cell adhesion postsynaptic density protein of 95 kDa (PSD-95) scaffold synapse Neuronal synapses are the key relay and modulation sites of signalling in the central nervous system. Consequently their molecular architecture and the properties...

... dimensions of the adherens junctions. Structure and Function in Cell Adhesion: Biochemical Society Annual Symposium No. 75 held at The Palace Hotel, Manchester, U.K., 3–5 December 2007. Organized and Edited by David Garrod (Manchester, U.K.). EM electron microscopy FN fibronectin type...

... bonds. The cumulative results demonstrate that cadherins adhere via a multistage binding mechanism that involves multiple extracellular domains. In kinetic measurements of cell adhesion, cell pairs first form a low-probability-binding state with fast kinetics. This is followed by a lag and a slow...

... catenin cell adhesion Cadherins are calcium-dependent cell adhesion molecules whose extracellular regions mediate homotypic cell–cell adhesion. The classical cadherins are found in adherens junctions, cell–cell contact structures that are associated with the actin cytoskeleton [ 1 , 2 ]. The co...

...Gethin Rh. Owen; Devrim Acehan; K.D. Derr; William J. Rice; David L. Stokes Desmosomes are a complex assembly of protein molecules that form at the cell surface and mediate cell–cell adhesion. Much is known about the composition of desmosomes and there is an established consensus for the location...

...Asoka Banno; Mark H. Ginsberg Agonist stimulation of integrin receptors, composed of transmembrane α and β subunits, leads cells to regulate integrin affinity (‘activation’), a process that controls cell adhesion and migration, and extracellular matrix assembly. A final step in integrin activation...

... in susceptible areas of the artery wall. 1 To whom correspondence should be addressed (email [email protected] ). 20 12 2006 © 2007 Biochemical Society 2007 atherosclerosis cell adhesion chylomicron remnant dietary fat monocyte reactive oxygen species It is well...

... original authors. J.W. is supported by the EC grant QLG3-CT-2002-01266. 1 To whom correspondence should be addressed (email [email protected] ). 6 7 2004 © 2004 The Biochemical Society 2004 adherens junction cell adhesion cell polarity Crumbs homologue 1 (CRB1) Leber...

... of force to focal adhesions results in the formation of fibrillar adhesions and reorganization of the extracellular matrix. The formation of these adhesions depends on actomyosin contractility and matrix pliability. Introduction Cell adhesion to the ECM (extracellular matrix) plays key roles...

... Molecular Environment of Integrins: a Biochemical Society Focused Meeting held at Chancellors Conference Centre, University of Manchester, 1–3 December 2003 3 December 2003 © 2004 Biochemical Society 2004 cell adhesion FERM domain integrin PTB domain talin Abbreviations...

...T. Chavakis; S. M. Kanse; A. E. May; K. T. Preissner Vascular cell adhesion and migration, proliferation or differentiation are cellular responses that are induced by haemostatic factors of the urokinase/plasminogen activation complex, but the respective underlying mechanisms are largely undefined...