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Keywords: cell engineering
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Biochem Soc Trans (2021) 49 (2): 915–931.
Published: 11 March 2021
... to be elucidated in order to determine a priori which glycoform is desirable for a specific biotherapeutic. The intimate structure-activity relationship (SAR) of N-glycans in a therapeutic context is perhaps best studied in monoclonal antibodies (mAbs) [ 8 ]. mAbs and their biosimilars cell engineering...
Biochem Soc Trans (2014) 42 (3): 679–687.
Published: 22 May 2014
... and in vivo settings in the future. cell engineering cell homing cell surface sensor immunomodulation mRNA transfection stem cell therapy Stem cell therapies hold great potential to treat a wide range of diseases and conditions including cardiovascular, neurodegenerative, bone and immune...
Biochem Soc Trans (2006) 34 (2): 301–303.
Published: 20 March 2006
... ]. Higher activities ultimately mean much reduced fermentation costs. Recently, work has been started on cell engineering, for example altering expression levels of multiple enzyme systems [ 26 ]. More work in this activity is required, in particular to devise more stable cells in industrial conditions...