... Press and the Biochemical Society under a transformative agreement with CAUL. cell proliferation cellular reproduction cytokinesis developmental biology DNA replication and recombination Drosophila melanogaster Although this review will focus on unusual modes of cell division...

... importance has been elucidated in NSCs by knockout or overexpression studies. We mainly discuss the transcription factors with roles in the active, quiescent, and rejuvenation states of adult NSCs. aging cell proliferation gene expression and regulation neural stem cells neurogenesis transcription...

... processes. While NRF2 activation affects most or even all cell types, its effect on epithelial cells during repair processes has been particularly well studied. In response to tissue injury, these cells proliferate, migrate and/or spread to effectively repair the damage. In this review, we discuss how NRF2...

... ( [email protected] ) * These authors contributed equally to this work. 28 1 2022 15 3 2022 21 3 2022 © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022 cell proliferation G-proteins GTPase oncogenesis RAS tumour...

.... cell proliferation evolution neocortex development neural progenitor cells neurogenesis The neocortex is the largest part of the mammalian cerebral cortex and is the seat of higher cognitive functions, such as thinking and language in human. The neocortex is characterized by six layers...

... article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bacteria cell proliferation cell wall membranes The cell wall is an almost ubiquitous feature of the domain Bacteria. The major...

.... Intriguingly, a number of studies have revealed that cleavage site selection is subject to global, directional modulation under certain conditions. In particular, the onset of cell proliferation is associated with a widespread shift towards preferential usage of proximal cleavage sites (3′UTR shortening...

... in different cellular contexts. This has led to their definition in the control of various cell functions, such as cell proliferation in the thyroid and actin cytoskeleton organization in fibroblasts and lymphocytes. Roles for the glycerophosphoinositols in immune and inflammatory responses are also being...

... activity that affected epithelial cell proliferation and protein synthesis was noted. This activity was termed UGIF [ 2 ]. Of interest, cancer cells, including the NBT (Nara Bladder Tumour)-II cells, were particularly responsive to UGIF activity. We noted that mesenchymal cells and adult prostate stromal...

...Cristina Mazzoni; Claudio Falcone Most of the studies on cell proliferation examine the control of gene expression by specific transcription factors that act on transcriptional initiation. In the last few years, it became evident that mRNA stability/turnover provides an important mechanism for post...

... of methylation reactions. Myc-induced cap methylation is a major effect of Myc function, being necessary for activated protein synthesis, cell proliferation and cell transformation. Inhibition of cap methylation is synthetic lethal with elevated Myc protein expression, which indicates the potential for cap...

... controlling cell proliferation and differentiation. Lamins affect the activity of several transcription factors, such as retinoblastoma protein and c-Fos, and signalling pathways, such as the ERK1/2 (extracellular-signal-regulated kinase 1/2) and Notch pathways, which are key regulators of cell-cycle...

...Marc Piechaczyk; Rosa Farràs JunB is a member of the AP-1 (activator protein-1) family of dimeric transcription factors. It exerts a dual action on the cell cycle. It is best known as a cell proliferation inhibitor, a senescence inducer and a tumour suppressor. As for the molecular mechanisms...

... Society 2008 cell differentiation cell proliferation mRNA translation Musashi protein neural stem cell Xenopus Musashi exerts translational repression of target mRNAs via a 5′-cap-dependent mechanism in neural stem cells, but paradoxically exerts target mRNA translational activation...

... hydrogels via hydrogen-bonding and π–π interactions from the fluorenyl rings. These highly hydrated gels allowed for cell proliferation of chondrocytes in three dimensions [Jayawarna, Ali, Jowitt, Miller, Saiani, Gough and Ulijn (2006) Adv. Mater. 18 , 611–614]. We demonstrated that fibrous architecture...

... using primary T-cells from SHIP1 −/− mice have highlighted a new role for SHIP1 in regulatory T-cell development, but also emphasize that this protein is not required for T-cell proliferation. In support of these results, SHIP1 −/− mice are lymphopenic, suggesting that SHIP1 function in T-cells differs...

... of the cell cycle. We investigated the effect of quinidine and caesium (Cs + ) on cell proliferation, LDH (lactate dehydrogenase) release, free internal calcium, membrane potential, polyamine concentration, ODC (ornithine decarboxylase) activity and polyamine uptake in C6 glioma cells. The EC 50 for reducing...

... 2006 apoptosis calcium cell differentiation cell proliferation prostate cancer transient receptor potential channel (TRP channel) PC (prostate cancer) is one of the leading threats to men's health. Its early stage depends on androgens for growth and survival, and androgen ablation...

... analysis of Arabidopsis TOR mutants indicates that the plant TOR pathway fulfils the same role in controlling cell growth as its other eukaryotic counterparts. In plants, cell proliferation occurs in meristems, dynamic structures continuously traversed by a flux of cells that divide and grow...

... arguments - (a) the decline with age in naive T cell proliferation despite their relatively long telomeres; (b) the preservation of T cell proliferation in Werner's syndrome patients despite their cell lines' proclivity to replicative senescence in vitro ; and (c) the ability of PMA and ionomycin...