..., we present quantitative data on how different antibiotic targets modulate cellular shape metrics including surface area, volume, surface-to-volume ratio, and the aspect ratio. Using recently developed quantitative models, we relate cell shape changes to alterations in the physiological state...

... of these proteases can convert cells undergoing mesenchymal type invasion to an amoeboid type, highlighting their plasticity [ 7 ]. Amoeboid movement is defined due to the changes in cell shape and inherent plasticity in which they can move through the ECM without requiring its remodelling [ 8 ]. Additionally...