... malaria protection from lack of malaria exposure in field studies. We also identify gaps in our knowledge regarding cellular immunity in the youngest age group and propose directions that researchers may take to address these gaps. Correspondence: Tuan M. Tran ( [email protected] ) 17 1 2024...

... cellular immunity. This is via their molecular interaction with important immune cell-surface molecules such as antigen-presenting MHC proteins, T-cell co-receptors CD4 and CD8, as well as cytoplasmic molecules such as Lck and PKC (protein kinase C). Moreover, the generation of tetraspanin-deficient mice...

... on MHCI and MHCII [ 2 ]. DCs are the most potent professional antigen-presenting cells, capable of 10–100-fold greater formation of peptide MHC complexes on their surfaces than other antigen-presenting cells [ 3 ], leading to greater T-cell activation, the hallmark of cellular immunity. DCs act...