1-10 of 10
Keywords: centromere
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem Soc Trans (2024) 52 (1): 455–464.
Published: 19 February 2024
...) . bookmarking centromere gene expression mitosis RNA Pol II transcription More than 60 years ago, Prescott and Bender [ 1 ] first reported a drastic silence of transcription during mitosis by using nascent RNA labeling in HeLa cells ( Figure 1A,B ). The underlying mechanisms remained unknown until...
Articles
Articles
Biochem Soc Trans (2013) 41 (6): 1706–1711.
Published: 20 November 2013
...Susan L. Forsburg Replication stress is a significant contributor to genome instability. Recent studies suggest that the centromere is particularly susceptible to replication stress and prone to rearrangements and genome damage, as well as chromosome loss. This effect is enhanced by loss...
Articles
Biochem Soc Trans (2013) 41 (6): 1726–1730.
Published: 20 November 2013
...Fekret Osman; Matthew C. Whitby Centromere proteins CENP-S and CENP-X are members of the constitutive centromere-associated network, which is a conserved group of proteins that are needed for the assembly and function of kinetochores at centromeres. Intriguingly CENP-S and CENP-X have alter egos...
Articles
Articles
Articles
Biochem Soc Trans (2010) 38 (6): 1660–1666.
Published: 24 November 2010
... in both pathways. In this review we focus on a poorly understood but important aspect of mitotic control: what prevents the mitotic checkpoint from springing into action when sister centromeres are split and tension is suddenly lost at anaphase onset? Recent work has shown that disjunction of sister...
Articles
Biochem Soc Trans (2010) 38 (6): 1667–1675.
Published: 24 November 2010
...Bernardo Orr; Olga Afonso; Tália Feijão; Claudio E. Sunkel The kinetochore is a complex molecular machine that serves as the interface between sister chromatids and the mitotic spindle. The kinetochore assembles at a particular chromosomal locus, the centromere, which is essential to maintain...
Articles
Biochem Soc Trans (2007) 35 (3): 609–611.
Published: 22 May 2007
...) and centromeres (red circles) are shown. ( B ) Schematic representation of the preferred positioning for 11 human chromosomes based on longitude/radial localization and inter-chromosomal distances. Another important characteristic of human sperm nuclear organization is the existence of a preferred...
Articles
Biochem Soc Trans (2004) 32 (6): 920–923.
Published: 26 October 2004
...R. Waldron; T. Moore The mouse jerky gene and its human orthologue, JRK / JH8 , encode a putative DNA-binding protein with homology to the CENP-B (centromere-binding protein B). Disruption of the mouse jerky gene by transgene insertion causes generalized recurrent seizures reminiscent of human...