... compilation © 2014 Biochemical Society 2014 bacterial moonlighting protein chaperonin glyceraldehyde-3-phosphate dehydrogenase (GAPDH) heat-shock protein pathogen Although bacteria are single-celled organisms, they signal to themselves, to other micro-organisms and to their eukaryotic hosts...

... are full of traps for the unwary: the forces that drive proteins into their folded states can also drive them into insoluble aggregates, and, particularly when cells are stressed, this can lead, without prevention or correction, to cell death. The chaperonins are a family of molecular chaperones...

...Andrew T. Large; Martin D. Goldberg; Peter A. Lund A survey of archaeal genomes for the presence of homologues of bacterial and eukaryotic chaperones reveals several interesting features. All archaea contain chaperonins, also known as Hsp60s (where Hsp is heat-shock protein). These are more similar...