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Keywords: co-translational folding
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Articles
How lipids affect the energetics of co-translational alpha helical membrane protein folding
Open Access
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 555–567.
Published: 25 February 2022
... membrane proteins, as well as how lipids can make these processes more or less favourable. We will also discuss the implications of this work for the free energy landscape during the co-translational folding of alpha helical membrane proteins. Figure 4. How bilayer properties affect the free energy...
Articles
Timing during translation matters: synonymous mutations in human pathologies influence protein folding and function
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (4): 937–944.
Published: 31 July 2018
...’ functional integrity begins co-translationally, during translation of messenger RNA into a nascent polypeptide. Growing evidence indicates that the rate at which ribosomes synthesize a polypeptide chain orchestrates co-translational folding, binding to other macromolecular entities (e.g. chaperones...