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Keywords: colitis
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Biochem Soc Trans (2014) 42 (6): 1524–1528.
Published: 17 November 2014
... a bigger hydrophobic pocket in PKCθ as compare with Phe 633 and Leu 355 (brown) in PKCδ. autoimmunity colitis experimental autoimmune encephalomyelitis (EAE) memory T-cell protein kinase Cθ (PKCθ) T-cell Protein kinase Cθ (PKCθ) is a member of a large family of serine/threonine...
Includes: Supplementary data
Biochem Soc Trans (2007) 35 (6): 1473–1478.
Published: 23 November 2007
... of TLR (Toll-like receptor) signalling in the healthy host and the diseased host. We pay particular attention to the role of TLR signalling in idiopathic IBD (inflammatory bowel disease) and colitis-associated carcinogenesis. In general, TLR signalling in health contributes to homoeostatic functions...
Biochem Soc Trans (2007) 35 (2): 167–171.
Published: 20 March 2007
..., we review the role of PI3Ks in T-cell development and function. colitis forkhead box O (Foxo) p110δ phosphoinositide 3-kinase (PI3K) T-cell thymocyte The PI3K p110δ plays a key role in the context of antigen receptor signalling. The dual impact of p110δ on Th and Treg development...