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Keywords: colorectal cancer
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Articles
Biochem Soc Trans (2022) 50 (1): 223–230.
Published: 15 February 2022
... the bioactivity of the IL-36 subfamily and its role in the pathogenesis of intestinal diseases such as inflammatory bowel disease, colorectal cancer, gut dysbacteriosis and infection, and proposes that IL-36 may be a target for novel therapeutic strategies to prevent or treat intestinal diseases...
Articles
Biochem Soc Trans (2016) 44 (6): 1683–1693.
Published: 02 December 2016
... on behalf of the Biochemical Society 2016 colorectal cancer endometrial cancer glioma LCMT-1 neuroendocrine prostate cancer PTPA Protein phosphorylation is a posttranslational modification (PTM) event, which is reversibly carried out by the action of phosphorylating protein kinases...
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Biochem Soc Trans (2008) 36 (6): 1350–1353.
Published: 19 November 2008
... as laminopathies. However, a new role for lamin A has been discovered in the progression of a common epithelial cancer. CRC (colorectal cancer) patients expressing lamin A/C in their tumour tissue were found to have a 2-fold greater risk of CRC-related mortality compared with patients with lamin A/C-negative...
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Biochem Soc Trans (2007) 35 (5): 1355–1357.
Published: 25 October 2007
...G.G.C. Kuhnle; S.A. Bingham Colorectal cancer is the third most common cancer in developed countries such as the U.K., but incidence rates around the world vary approx. 20-fold. Diet is thought to be a key factor determining risk: red and processed meat, but not white meat or fish, are associated...
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Biochem Soc Trans (2007) 35 (2): 364–368.
Published: 20 March 2007
...F.R. Saunders; H.M. Wallace Colorectal cancer is one of a number of cancers that may be amenable to prevention. The NSAIDs (non-steroidal anti-inflammatory drugs) have been shown to be effective chemopreventative agents in humans, but their mechanism of action is not clear. The polyamines...
Articles
Biochem Soc Trans (2005) 33 (4): 689–693.
Published: 01 August 2005
...S.J. Scherer; E. Avdievich; W. Edelmann Mutations in MMR (DNA mismatch repair) genes underlie HNPCC (hereditary non-polyposis colon cancer) and also a significant proportion of sporadic colorectal cancers. MMR maintains genome stability and suppresses tumour formation by correcting DNA replication...
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Biochem Soc Trans (2005) 33 (4): 694–697.
Published: 01 August 2005
.... The Molecular Biology of Colorectal Cancer: Focused Meeting held at the UBHT Education Centre, Bristol, U.K., 10–11 March 2005. Organized and edited by T. Corfield (Bristol, U.K.), C. Paraskeva (Bristol, U.K.) and H. Wallace (Aberdeen, U.K.). APC adenomatous polyposis coli Asef APC-stimulated...
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Biochem Soc Trans (2005) 33 (4): 701–704.
Published: 01 August 2005
... is a highly promising agent for the prevention and/or treatment of cancer. 1 To whom correspondence should be addressed (email kashfi@med.cuny.edu ). 22 3 2005 © 2005 The Biochemical Society 2005 apoptosis colorectal cancer COX-2 (cyclo-oxygenase-2) NF-κB (nuclear factor κB...
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Biochem Soc Trans (2005) 33 (4): 684–688.
Published: 01 August 2005
... detection markers or potentially risk stratification markers remains under active investigation. The Molecular Biology of Colorectal Cancer: Focused Meeting held at the UBHT Education Centre, Bristol, U.K., 10–11 March 2005. Organized and edited by T. Corfield (Bristol, U.K.), C. Paraskeva (Bristol...
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Articles
Biochem Soc Trans (2005) 33 (4): 679–683.
Published: 01 August 2005
... should be addressed (email sampson@cardiff.ac.uk ). 29 3 2005 © 2005 The Biochemical Society 2005 adenomatous polyposis coli (APC) colorectal cancer familial adenomatous polyposis (FAP) MutYH (MYH) MutYH-associated polyposis (MAP) Most CRCs (colorectal cancers) are thought...
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Biochem Soc Trans (2005) 33 (4): 665–666.
Published: 01 August 2005
... (familial adenomatous polyposis), an autosomal syndrome that is characterized by multiple colorectal lesions [ 1 ]. APC is also mutated in the majority of sporadic colorectal cancers, and inactivation of APC is recognized as a key early genetic change in colorectal tumorigenesis. This has given rise...