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Keywords: condensate
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1809–1825.
Published: 03 July 2024
...Ruaridh Lang; Rachel E. Hodgson; Tatyana A. Shelkovnikova TDP-43 is an abundant and ubiquitously expressed nuclear protein that becomes dysfunctional in a spectrum of neurodegenerative diseases. TDP-43's ability to phase separate and form/enter biomolecular condensates of varying size...
Articles
A closer look at mammalian antiviral condensates
Open Access
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1393–1404.
Published: 23 May 2024
...J. Monty Watkins; James M. Burke Several biomolecular condensates assemble in mammalian cells in response to viral infection. The most studied of these are stress granules (SGs), which have been proposed to promote antiviral innate immune signaling pathways, including the RLR-MAVS, the protein...