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Keywords: conditional gene expression
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Biochem Soc Trans (2005) 33 (3): 474–476.
Published: 01 June 2005
...B. Suess We have developed conditional gene expression systems based on engineered small-molecule-binding riboswitches. Tetracycline-dependent regulation can be imposed on an mRNA in yeast by inserting an aptamer in its 5′-untranslated region. Biochemical and genetic analyses determined that...