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Keywords: connexin
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Articles
Biochem Soc Trans (2015) 43 (3): 460–464.
Published: 01 June 2015
... with the hypothesis that carbamate bond formation is responsible for channel opening in Cx26. For carbamate bond formation to be important there must be a CO 2 binding site. Sequence comparison of the CO 2 sensitive connexins (26, 30 and 32) to the non-sensitive Cx31 indicated one lysine residue, lysine 125...
Articles
Biochem Soc Trans (2015) 43 (3): 519–523.
Published: 01 June 2015
... of connexin 43 channels is regulated through protein kinase C-dependent phosphorylation Circ. Res. 2006 98 1498 1505 10.1161/01.RES.0000227572.45891.2c 16709897 10 Shah M.M. Martinez A.M. Fletcher W.H. The connexin43 gap junction protein is phosphorylated by protein kinase...
Articles
Biochem Soc Trans (2015) 43 (3): 524–529.
Published: 01 June 2015
..., endothelial dysfunction can lead to hyperplasia of the underlying medial layer. Connexins are a family of transmembrane proteins which can form intercellular communication channels known as gap junctions. This review will discuss recent evidence which shows that connexins play a role in regulation...
Articles
Biochem Soc Trans (2015) 43 (3): 513–518.
Published: 01 June 2015
... contraction. Twelve connexin (Cx) proteins make up one gap junction channel, of which there are three main subtypes in the heart; Cx40, Cx43 and Cx45. In the cardiac myocyte, gap junctions are present mainly at the intercalated discs between neighbouring myocytes, and assist in rapid electrical conduction...
Articles
Biochem Soc Trans (2015) 43 (3): 447–449.
Published: 01 June 2015
... of the highlights of the work discussed throughout the day. 1 To whom correspondence should be addressed (email: patricia.martin@gcu.ac.uk ) . 5 2 2015 © The Authors Journal compilation © 2015 Biochemical Society 2015 connexin pannexin gap junction The UK Gap Junction...
Articles
Biochem Soc Trans (2015) 43 (3): 489–494.
Published: 01 June 2015
.... Given the role of gap junctions in the co-ordination of tissue responses, it was hypothesized that gap junctions may be present within a thrombus and mediate intercellular communication between platelets. Therefore studies were performed to explore the presence and functions of connexins in platelets...