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Keywords: context-dependence
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Articles
Fuzzy protein theory for disordered proteins
Open Access
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2557–2564.
Published: 10 November 2020
... components of condensates, termed as clients, require a partner-induced change in their binding modes. These proteins exhibit fuzzy binding and shift from ordered to disordered bound states in a context-dependent manner [ 27 ]. Aging or familial mutations can induce the conversion of liquid droplets...