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Keywords: cullin-RING ligases
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Biochem Soc Trans (2021) 49 (1): 519–529.
Published: 05 February 2021
... of specific substrate proteins for polyubiquitination. Really interesting new gene (RING) finger E3s account for the majority of E3s. The human genome encodes more than 600 RING E3s, which are divided into three subclasses: single polypeptide E3s, cullin-RING ligases (CRLs) and other multisubunit E3s...