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Keywords: cybrid
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Biochem Soc Trans (2013) 41 (1): 118–123.
Published: 29 January 2013
... 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 cybrid cytochrome c redox signalling platelet mitochondria The traditional view of the mitochondrion as the ‘powerhouse’ of the cell has greatly evolved over the last few decades. It is now clear...
Biochem Soc Trans (2006) 34 (5): 824–827.
Published: 25 October 2006
... in mitochondrial function. Recently, we used clonal cytosolic hybrid cells (namely cybrids) harbouring mitochondria derived from MIDD patients. Compared with control mtDNA from the same patient, the A3243G mutation markedly modified metabolic pathways. Moreover, cybrid cells carrying patient-derived mutant mtDNA...