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Keywords: cyclo-oxygenase
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Biochem Soc Trans (2008) 36 (5): 1055–1059.
Published: 19 September 2008
...Benjamin H. Maskrey; Valerie B. O'Donnell Eicosanoids are oxidized arachidonate-derived lipids products generated by lipoxygenase, cyclo-oxygenase and cytochrome P450. Their bioactivity is mediated via receptor-dependent mechanisms and they are involved in a diverse array of processes in both...
Biochem Soc Trans (2008) 36 (5): 955–958.
Published: 19 September 2008
.... In the present review, we focus on exogenous and endogenous effects of NEFAs, including the polyunsaturated fatty acid, arachidonic acid (or its metabolites generated from cyclo-oxygenase activity), on β-cell metabolism, and have explored the outcomes with respect to β-cell insulin secretion. Insulin...
Biochem Soc Trans (2004) 32 (6): 1078–1080.
Published: 26 October 2004
...K.M. Fang; W.H. Shu; H.C. Chang; J.J. Wang; O.T. Mak PGs (prostaglandins) are synthesized through the cyclo-oxygenase (COX-1 and -2) pathway in a variety of cells in response to various physiological stimuli. All cells require at least one pathway for apoptosis, and mitochondrial play a central...
Biochem Soc Trans (2004) 32 (1): 110–112.
Published: 01 February 2004
...-cell function to generate a pro-atherogenic phenotype, the mechanisms involved remain undefined. We have examined the effects of CMR-like particles (CMR-LPs) on human endothelial-cell function, focusing on the cyclo-oxygenase (COX) and nitric oxide synthase (NOS) pathways. CMR-LPs strongly enhanced...