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1-6 of 6
Keywords: cystic fibrosis transmembrane conductance regulator (CFTR)
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Articles
Learning from each other: ABC transporter regulation by protein phosphorylation in plant and mammalian systems
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (5): 966–974.
Published: 09 October 2015
... events of human cystic fibrosis transmembrane conductance regulator (CFTR) and ABCB1 from the model plant Arabidopsis reveals a surprisingly high degree of similarity. Both physically interact with orthologues of the FK506-binding proteins that chaperon both transporters to the plasma membrane...
Articles
Exploiting species differences to understand the CFTR Cl − channel
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (5): 975–982.
Published: 09 October 2015
...Samuel J. Bose; Toby S. Scott-Ward; Zhiwei Cai; David N. Sheppard The anion channel cystic fibrosis transmembrane conductance regulator (CFTR) is a unique ATP-binding cassette (ABC) transporter. CFTR plays a pivotal role in transepithelial ion transport as its dysfunction in the genetic disease...
Includes: Supplementary data
Articles
Intestinal inflammation and the enterocyte transportome
Available to PurchaseIsabel Romero-Calvo, Cristina Mascaraque, Antonio Zarzuelo, María Dolores Suárez, Olga Martínez-Augustin, Fermín Sánchez de Medina
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (4): 1096–1101.
Published: 20 July 2011
.... Steinbrecher K.A. Rothenberg M.E. Shroyer N.F. Matthaei K.I. Interleukin-13 (IL-13)/IL-13 receptor α1 (IL-13Rα1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator (CFTR) channel-dependent Cl− secretion J. Biol. Chem. 2011 286 13357 13369...
Articles
Novel regulatory mechanisms for the CFTR gene
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (4): 843–848.
Published: 22 July 2009
... (3C) cortactin-binding protein 2 (CTTNBP2) cystic fibrosis transmembrane conductance regulator (CFTR) DNase I-hypersensitive site (DHS) The CFTR (cystic fibrosis transmembrane conductance regulator) gene encompasses 189 kb at chromosome 7q31.2 [ 1 ]. CFTR is flanked on the 5′ side...
Articles
Crystallographic and single-particle analyses of native- and nucleotide-bound forms of the cystic fibrosis transmembrane conductance regulator (CFTR) protein
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (5): 996–999.
Published: 26 October 2005
... of the protein was observed in the quiescent (nucleotide-free) state. © 2005 The Biochemical Society 2005 ATP-binding cassette (ABC) cystic fibrosis transmembrane conductance regulator (CFTR) crystallization membrane protein single-particle analysis three-dimensional structure The ABC (ATP...
Articles
Control of the CFTR channel's gates
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (5): 1003–1007.
Published: 26 October 2005
...-binding cassette protein (ABC protein) cystic fibrosis transmembrane conductance regulator (CFTR) heterodimer single-channel kinetics nucleotide-binding domain Cystic fibrosis is the most common lethal genetic disease in Caucasian populations. It is caused by mutations in the CFTR gene...