... ). 1 11 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 cardiolipin cytosol endoplasmic reticulum (ER) endoplasmic reticulum–mitochondria encounter structure (ERMES) lipid binding mitochondrion The eukaryotic cell is a highly complex entity that carries...

... state have been lost and others relinquished to the host nucleus. The extensive movement of genetic information to the nucleus means that a majority of plastid proteins are now translated on cytosolic ribosomes and plastid targeting is essential to ensure that plastid proteins are reimported...

...Luis C. Antón; Eugenia M. Villasevil While it is clear that the proteasome is the major player in degradative proteolysis in the nucleus and cytosol, there is a lack of complete agreement on whether there are alternative proteolytic pathways or activities responsible for a significant degradation...

..., pathogenic bacteria have devised a mechanism to transfer toxic adenylate cyclases into eukaryotic cells and generate a cytosolic pool of cAMP that disrupts the barrier. To determine whether membrane or cytosolic cAMP synthesis dominates in control of endothelial cell barrier function, we expressed a soluble...

... that Nar1p is an Fe-S protein and that assembly of its co-factors depends on the mitochondrial Fe-S cluster biosynthesis apparatus. Using functional studies in vivo , we demonstrated that Nar1p has an essential role in the maturation of cytosolic and nuclear, but not of mitochondrial, Fe-S proteins [Balk...

... in the cytosol, and is not detectable in the plastids, mitochondria or peroxisomes. During seed development, ACL-A and ACL-B mRNA accumulation is co-ordinated with the accumulation of the cytosolic homomeric acetyl-CoA carboxylase mRNA. Antisense Arabidopsis plants reduced in ATP citrate lyase activity show...