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Keywords: dual-specificity phosphatases
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Articles

The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases

Andrew R. Clark, Jonathan L.E. Dean
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (5): 1321–1337.
https://doi.org/10.1042/BST20160166
Published: 19 October 2016
... negative feedback mechanism involves dual-specificity phosphatase 1 (DUSP1, also known as MAPK phosphatase 1 or MKP-1) [ 42 – 44 ]. DUSP1 is normally expressed at very low levels in resting cells. Pro-inflammatory stimuli increase its expression in an MAPK p38-dependent manner. It then dephosphorylates...
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Articles

Regulatory mechanisms of phosphatase of regenerating liver (PRL)-3

Teresa Rubio, Maja Köhn
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (5): 1305–1312.
https://doi.org/10.1042/BST20160146
Published: 19 October 2016
... © 2016 The Author(s) 2016 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cancer dual-specificity phosphatases metastasis post-translational modification...
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