... complex in pluripotency and cell lineage primining and the approaches that have helped delineate its importance. Understanding these molecular mechanisms is crucial for unraveling the intricate processes governing embryonic stem cell biology and developmental transitions and may potentially apply to human...

...Qiyu Tian; Hoyoung Chung; Duancheng Wen Pluripotent stem cells (PSCs), comprising embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), offer immense potential for regenerative medicine due to their ability to differentiate into all cell types of the adult body. A critical aspect...

... differentiation embryonic stem cells gene expression RNA cap RNMT Uncovering the molecular mechanisms operating in embryonic stem (ES) cells is critical for our understanding of development and many disease states, and for the use of these cells in therapeutics. The function and fate of ES cells...

... network of embryonic stem cells (ESCs) since they induce genes necessary to maintain the undifferentiated state and repress others that promote differentiation [ 14–16 ]. Advances in the field showed that both, the maintenance of pluripotency and controlled cell fate transitions require a precise...