... 2014 Biochemical Society 2014 chronic kidney disease (CKD) endoplasmic reticulum stress (ER stress) glycation hypoxia proteostasis unfolded protein response (UPR) Protein homoeostasis, or proteostasis, is conducted through sophisticated networks of mechanisms to maintain the quality...

... mutation, as inflammation develops, the molecular markers of ER stress increase further and goblet cell pathology becomes worse, suggesting that inflammation itself exacerbates ER stress. endoplasmic reticulum stress (ER stress) goblet cell inflammatory bowel disease (IBD) MUC2 mucin misfolding...

... compilation © 2011 Biochemical Society 2011 endoplasmic reticulum stress (ER stress) inflammatory bowel disease (IBD) intestinal epithelial cell protein misfolding unfolded protein response (UPR) xenobiotic Chaperones and heat-shock proteins mediate protein folding inside the ER. For example...

... reticulum stress (ER stress) insulin lipotoxicity pancreatic β-cell 1 To whom correspondence should be addressed (email [email protected] ). 11 6 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 Following our electron microscopy observation that NEFAs...