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Keywords: epitranscriptome
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Biochem Soc Trans (2023) 51 (2): 783–796.
Published: 04 April 2023
... driving the ageing process. More than 170 chemical RNA modifications, also known as the epitranscriptome, decorate eukaryotic coding and non-coding RNAs and have emerged as novel regulators of RNA metabolism, modulating RNA stability, translation, splicing or non-coding RNA processing. Studies on short...
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Biochem Soc Trans (2017) 45 (4): 1007–1014.
Published: 14 July 2017
... to form the epitranscriptome. These modifications provide an additional layer of information to regulate protein synthesis by altering the translation efficiencies of individual messages [ 53 ]. Capping of newly transcribed pre-mRNAs represents a crucial event as transcripts are predominantly...
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Biochem Soc Trans (2016) 44 (5): 1385–1393.
Published: 19 October 2016
... revealed a dynamic landscape of the ‘Epitranscriptome’ for many mRNA modifications in various organisms from yeast to humans. Meanwhile, also many genes encoding mRNA-modifying enzymes and auxiliary proteins have been identified yielding functional insights by reverse genetics into their role...