... driving the ageing process. More than 170 chemical RNA modifications, also known as the epitranscriptome, decorate eukaryotic coding and non-coding RNAs and have emerged as novel regulators of RNA metabolism, modulating RNA stability, translation, splicing or non-coding RNA processing. Studies on short...

... gene expression, AS events, splice isoforms, APA, Poly(A) + length, alternative TSS, epitranscriptome, and novel chimeric genes. The picture of Nanopore GridION is downloaded from https://nanoporetech.com/products/gridion #. The asterisks indicate that the corresponding platform is either not widely...

... 13 6 2017 14 6 2017 © 2017 The Author(s) 2017 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . epitranscriptome RNA-binding proteins stress...

... revealed a dynamic landscape of the ‘Epitranscriptome’ for many mRNA modifications in various organisms from yeast to humans. Meanwhile, also many genes encoding mRNA-modifying enzymes and auxiliary proteins have been identified yielding functional insights by reverse genetics into their role...