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Keywords: extracellular loopClose
Journal: Biochemical Society Transactions
Biochem Soc Trans (2002) 30 (4): 437–441.
Published: 01 August 2002
... interacted with an arginine residue in transmembrane helix 2 (TM2) of the receptor, and the lysine residue in extracellular loop 1 (ECL1) stabilized the active receptor conformation induced by the ligand. The glucagon receptor possesses a Lys instead of an Arg in TM2, and an Ile instead of Lys in ECL1...