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Keywords: fibroblast-like synoviocyte
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Articles

The role of histone deacetylases in rheumatoid arthritis fibroblast-like synoviocytes

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Sarah Hawtree, Munitta Muthana, Anthony G. Wilson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (3): 783–788.
https://doi.org/10.1042/BST20130053
Published: 23 May 2013
...Sarah Hawtree; Munitta Muthana; Anthony G. Wilson RA (rheumatoid arthritis) is an inflammatory disease of synovial joints affecting approximately 1% of the population. One of the main cell types involved in damage to RA joint tissue is the FLSs (fibroblast-like synoviocytes). These have a semi...
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Articles

Phosphoinositide 3-kinase signalling and FoxO transcription factors in rheumatoid arthritis

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K.A. Reedquist, J. Ludikhuize, P.P. Tak
Journal: Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 727–730.
https://doi.org/10.1042/BST0340727
Published: 25 October 2006
... of inflammation and eventual joint destruction through activation of stromal fibroblast-like synoviocytes. Fundamental studies in developmental biology, cellular biology and immunology have established critical roles for PI3K (phosphoinositide 3-kinase) signal transduction pathways in cellular chemotactic...
View articletitled, Phosphoinositide 3-kinase signalling and FoxO transcription factors in rheumatoid arthritis
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