... by approx. 50%, suggesting that, as well as apoE-mediated endocytic uptake, apoE receptor-independent mechanisms are involved in the induction of foam cells by chylomicron remnants. Evaluation of the radioactivity associated with macrophages after incubation with CRLPs containing radiolabelled lipids...

... in CMs (chylomicrons), which can be taken up by macrophages without need of further oxidation, leading to the formation of foam cells and initiating or aggravating the atherogenic process. Evidence from different studies has shown that dietary fat can influence the composition and size of TRLs...

... 2004 Biochemical Society 2004 antioxidant atherogenesis atherosclerosis foam cell lipoprotein oxidation macrophage Abbreviations used: LDL(R), low-density lipoprotein (receptor); SR-A, scavenger receptor class-A; apoB, apolipoprotein B; αTOH, α-tocopherol; 7KC, 7-ketocholesterol...