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Keywords: fructoselysine
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Biochem Soc Trans (2003) 31 (6): 1426–1427.
Published: 01 December 2003
...W.E. Cotham; D.J.S. Hinton; T.O. Metz; J.W.C. Brock; S.R. Thorpe; J.W. Baynes; J.M. Ames RNase A (1 mM) was incubated with glucose (0.4 M) at 37°C for up to 14 days in phosphate buffer (0.2 M, pH 7.4), digested with trypsin and analysed by LC-MS. The major sites of fructoselysine formation were Lys...
Biochem Soc Trans (2003) 31 (6): 1428–1432.
Published: 01 December 2003
... hypothesis, some outstanding issues remain. These include, among others, the fact that while the apparent deglycation mechanism does not operate on l -glucose, semi-purified FN3K appears to be able to use both d- and l -fructosamines as substrates. Moreover, analysis of the fructoselysine 3-phosphate content...