... 29 4 2021 30 4 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 enhancers genome organization optical nanoscopy single-molecule approaches transcription Enhancers are cis -regulatory elements that activate target...

... of this review, these questions will be considered, in light of the current literature regarding the role of transcription factories and the nuclear matrix in interphase genome organization. 1 To whom correspondence should be addressed (email joanna.bridger@brunel.ac.uk ). 30 7 2009 ©...

... capture (3C) chromosome organization genome organization locus control region transcription factory The sequence of the human genome has now been obtained, but the way DNA with a contour length of approx. 2 m might be compressed into a nucleus approx. 200000 times smaller is still a matter...

... & Beit Building South, Groote Schuur Campus, Observatory, 7925 Cape Town, South Africa. 2 To whom correspondence should be addressed (email peter.cook@path.ox.ac.uk ). 20 6 2006 © 2006 The Biochemical Society 2006 cell differentiation chromatin loop genome organization RNA...

..., U.S.A. 2 To whom correspondence should be addressed (email Joanna.Bridger@brunel.ac.uk ). 5 7 2005 © 2005 The Biochemical Society 2005 A-type lamin chromosome positioning genome organization laminopathy lymphoblastoid cell nuclear architecture Interphase...