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Keywords: genomic instability
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (03): 565–577.
Published: 16 May 2025
... uncovered novel oncogenic functions of the HPV oncoproteins, including the manipulation of emerging mechanisms of cancer development, such as epigenetic modifications, cellular plasticity and genomic instability. This review explores current advances in understanding how the HPV oncoproteins interact...
Articles
A tough row to hoe: when replication forks encounter DNA damage
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (6): 1643–1651.
Published: 04 December 2018
... protective measures are not executed. Stabilization and protection of stalled replication forks ensures the possibility of effective fork restart and prevents genomic instability. Recent efforts from multiple laboratories have highlighted several proteins involved in replication fork remodeling and DNA...