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Keywords: glucagon-like peptide-1 receptor
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Articles

The complexity of signalling mediated by the glucagon-like peptide-1 receptor

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Madeleine M. Fletcher, Michelle L. Halls, Arthur Christopoulos, Patrick M. Sexton, Denise Wootten
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (2): 582–588.
https://doi.org/10.1042/BST20150244
Published: 11 April 2016
...Madeleine M. Fletcher; Michelle L. Halls; Arthur Christopoulos; Patrick M. Sexton; Denise Wootten The glucagon-like peptide-1 receptor (GLP-1R) is a class B GPCR that is a major therapeutic target for the treatment of type 2 diabetes. The receptor is activated by the incretin peptide GLP-1...
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Articles

Recent advances in understanding GLP-1R (glucagon-like peptide-1 receptor) function

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Cassandra Koole, Kavita Pabreja, Emilia E. Savage, Denise Wootten, Sebastian G.B. Furness, Laurence J. Miller, Arthur Christopoulos, Patrick M. Sexton
Journal: Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (1): 172–179.
https://doi.org/10.1042/BST20120236
Published: 29 January 2013
[email protected] ). 24 9 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 allosteric modulation biased signalling G-protein-coupled receptor glucagon-like peptide-1 receptor glucagon-like peptide-1 probe-dependence Type 2 DM (diabetes mellitus) is a global...
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