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Keywords: glycobiology
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Articles
Identification, function, and biological relevance of POGLUT2 and POGLUT3
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 1003–1012.
Published: 11 April 2022
... between these two enzymes. 24 2 2022 25 3 2022 28 3 2022 © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022 extracellular matrix fibrillins glycobiology glycosylation LTBPs Addition of glucose or fucose...
Articles
Transgenic mouse models to study the physiological and pathophysiological roles of human Siglecs
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 935–950.
Published: 06 April 2022
...: Matthew S. Macauley ( [email protected] ) 20 1 2022 14 3 2022 18 3 2022 © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022 glycobiology humanized mice immune checkpoint sialic acid Siglec transgenic mice Siglecs...
Articles
Thomas Peters, Robert Creutznacher, Thorben Maass, Alvaro Mallagaray, Patrick Ogrissek, Stefan Taube, Lars Thiede, Charlotte Uetrecht
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 347–359.
Published: 23 December 2021
... The Author(s) 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . binding affinity glycobiology mass spectrometry nmr spectroscopy norovirus...
Articles
The Hitchhiker's guide to glycoproteomics
Open Access
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1643–1662.
Published: 20 July 2021
... making glycoproteins important diagnostic and prognostic biomarker candidates and therapeutic targets. Glycoproteomics, the study of glycans and their carrier proteins in a system-wide context, is becoming a powerful tool in glycobiology that enables the functional analysis of protein glycosylation...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 903–913.
Published: 16 April 2021
... — is dynamic and will vary in response to changes in the physiological state of the cell. Tools and techniques that help us characterise glycans and modulate their function in a native cellular context offer great opportunities to advance our understanding of glycobiology and can provide avenues...
Articles
History and future of shotgun glycomics
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2019) 47 (1): 1–11.
Published: 09 January 2019
... of the Biochemical Society 2019 glycan-binding proteins glycobiology glycomics microarrays shotgun glycomics The surfaces of all living cells comprises a heterogeneous assortment of macromolecules that provides an interface of cells with their aqueous environment. Glycans that comprise...
Articles
Harnessing post-translational modifications for next-generation HIV immunogens
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (3): 691–698.
Published: 21 May 2018
... The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 glycobiology glycosylation immunogen vaccine virus Innovations towards the development of bnAb-eliciting immunogens have included the production of native-like trimers that mimic the envelope (Env...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (2): 571–582.
Published: 13 April 2017
... BY) . calnexin drug discovery and design glucosidase glycobiology iminosugar Enveloped viruses have a membrane surrounding their capsid, which is composed of lipids derived from host membranes and viral glycoproteins. These viral glycoproteins are typically dependent upon the host endoplasmic...
Articles
Carbohydrate-active enzymes: sequences, shapes, contortions and cells
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (1): 79–87.
Published: 09 February 2016
... Press Limited 2016 biofuels conformational analysis drug design glycobiology glycosidase structural biology Glycans are found almost everywhere, and the enzymes that synthesize, modify and degrade these complex molecules are central to human health and disease and our modern...
Articles
Structural Glycobiology and Human Health
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (5): 1329–1332.
Published: 24 September 2010
...Barbara Mulloy; Anthony P. Corfield The glycans (carbonhydrates) form a diverse group of biomolecules which play active parts in most physiological processes. The field of structural glycobiology concerns the structures of the glycans themselves, the proteins which interact with them and the nature...