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1-6 of 6
Keywords: glycomics
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Articles
The Hitchhiker's guide to glycoproteomics
Open Access
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1643–1662.
Published: 20 July 2021
... analysis. Stage III : Online separation and fragmentation-based identification of glycopeptides. Stage IV : Bioinformatic (operator supervised) analyses of the data generated and integration of orthogonal data (e.g. glycomics data) to perform qualitative and quantitative glycoproteome profiling. Stage V...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 915–931.
Published: 11 March 2021
... under a transformative agreement with JISC. cell engineering erythropoietin glycomics glycoproteomics glycosylation monoclonal antibodies Advances in glycoengineering are increasingly providing opportunities for modulating the properties and functions of recombinant biotherapeutics...
Articles
A mass spectrometry-based glycotope-centric cellular glycomics is the more fruitful way forward to see the forest for the trees
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 55–69.
Published: 25 January 2021
...Kay-Hooi Khoo The nature of protein glycosylation renders cellular glycomics a very challenging task in having to deal with all the disparate glycans carried on membrane glycoproteins. Rapid mapping by mass spectrometry analysis provides only a coarse sketch of the glycomic complexity based...
Articles
History and future of shotgun glycomics
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2019) 47 (1): 1–11.
Published: 09 January 2019
... concentrations. The shotgun glycan microarray is then interrogated with a biologically relevant GBP and the corresponding glycan ligands can be retrieved from the TGL for detailed structural analysis and further functional analysis. Shotgun glycomics extended the defined glycan microarray to a discovery platform...
Articles
Heparan sulfate glycomics: towards systems biology strategies
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (5): 1356–1360.
Published: 24 September 2010
... requires the development of a holistic systems biology view of their structure and interactions. In the present paper, I describe some of the new tools available to realize this strategy, and discuss the future potential for the combined application of glycomics and other ‘-omics’ approaches to define...
Articles
Developing chemokine mutants with improved proteoglycan affinity and knocked-out GPCR activity as anti-inflammatory recombinant drugs
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (3): 435–437.
Published: 22 May 2006
... Society 2006 anti-inflammatory drug chemokine mutant glycomics glycosaminoglycan G-protein-coupled receptor (GPCR) protein engineering Chemokines induce cell migration and activation by binding to specific cell surface, seven-transmembrane-spanning GPCRs (G-protein-coupled receptors...