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Keywords: glycomics
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Articles
Biochem Soc Trans (2021) 49 (2): 915–931.
Published: 11 March 2021
... under a transformative agreement with JISC. cell engineering erythropoietin glycomics glycoproteomics glycosylation monoclonal antibodies Advances in glycoengineering are increasingly providing opportunities for modulating the properties and functions of recombinant biotherapeutics...
Articles
Biochem Soc Trans (2021) 49 (1): 55–69.
Published: 25 January 2021
...Kay-Hooi Khoo The nature of protein glycosylation renders cellular glycomics a very challenging task in having to deal with all the disparate glycans carried on membrane glycoproteins. Rapid mapping by mass spectrometry analysis provides only a coarse sketch of the glycomic complexity based...
Articles
Biochem Soc Trans (2019) 47 (1): 1–11.
Published: 09 January 2019
... concentrations. The shotgun glycan microarray is then interrogated with a biologically relevant GBP and the corresponding glycan ligands can be retrieved from the TGL for detailed structural analysis and further functional analysis. Shotgun glycomics extended the defined glycan microarray to a discovery platform...
Articles
Biochem Soc Trans (2010) 38 (5): 1356–1360.
Published: 24 September 2010
... requires the development of a holistic systems biology view of their structure and interactions. In the present paper, I describe some of the new tools available to realize this strategy, and discuss the future potential for the combined application of glycomics and other ‘-omics’ approaches to define the...
Articles
Biochem Soc Trans (2006) 34 (3): 435–437.
Published: 22 May 2006
... Society 2006 anti-inflammatory drug chemokine mutant glycomics glycosaminoglycan G-protein-coupled receptor (GPCR) protein engineering Chemokines induce cell migration and activation by binding to specific cell surface, seven-transmembrane-spanning GPCRs (G-protein-coupled receptors) on...