... experimental results obtained with DAG analogues could be reviewed in light of these findings. 1 email [email protected] 27 6 2006 © 2006 The Biochemical Society 2006 diacylglycerol guanine nucleotide-exchange factor (GEF) lymphocyte Ras guanine nucleotide releasing protein...

... initiation factor 2B (eIF2B) guanine nucleotide-exchange factor (GEF) leukodystrophy translation translation regulation Translation initiation in mammalian cells is a complex process that involves a set of proteins, the eukaryotic initiation factors (eIF). eIF2B, owing to its GEF (guanine...

... that may be explored for their inhibition. 1 To whom correspondence should be addressed (email [email protected] ). 22 6 2005 © 2005 The Biochemical Society 2005 Arf–Sec7 Brefeldin A (BFA) Golgi guanine nucleotide-exchange factor (GEF) membrane traffic small GTP...

... disease cAMP exchange protein directly activated by cAMP (EPAC) guanine nucleotide-exchange factor (GEF) protein kinase A (PKA) Rap Although the effects of cAMP-mediated signalling are wide ranging, there are only two general cAMP effectors, i.e. proteins that are activated by binding to cAMP...

...) guanine nucleotide-exchange factor (GEF) translation initiation In most schemes for translation initiation, eIF2B (eukaryotic initiation factor 2B) is usually depicted as facilitating either the first or the last step and as acting free from the ribosome itself. I usually like to think...

... at the cell membranes now become detectable. They should provide valuable tools for future investigations of the dynamics of membrane extraction or delivery of Rho proteins and their regulation by cellular partners. © 2005 The Biochemical Society 2005 Cdc42 Golgi guanine nucleotide-exchange factor...

... with a compartment-specific receptor. 1 To whom correspondence should be addressed (email [email protected] ). Arf protein Brefeldin A E/K mutation GDP/GTP exchange guanine nucleotide-exchange factor (GEF) Sec 7 domain Small GTP-binding proteins of the Arf family are major regulators...