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1-8 of 8
Keywords: guanine-nucleotide-exchange factor (GEF)
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Articles
Cdc42 regulates polarized growth and cell integrity in fission yeast
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (1): 201–205.
Published: 23 January 2014
... compilation © 2014 Biochemical Society 2014 Cdc42 cytoskeleton GTPase-activating protein (GAP) guanine-nucleotide-exchange factor (GEF) morphogenesis polarized growth secretion Recent work has established the collaborative role of Rga4 and Scd1–Scd2 in the regulation cell diameter [ 29...
Articles
cAMP signalling in the vasculature: the role of Epac (exchange protein directly activated by cAMP)
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (1): 89–97.
Published: 23 January 2014
... endothelial barrier function exchange protein directly activated by cAMP (Epac) guanine-nucleotide-exchange factor (GEF) protein kinase A (PKA) vascular smooth muscle vasculature vasodilatation The second messenger cAMP controls a range of vascular processes, including endothelial barrier...
Articles
Rab GTPase localization and Rab cascades in Golgi transport
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (6): 1373–1377.
Published: 21 November 2012
...) guanine-nucleotide-dissociation inhibitor (GDI) Golgi complex GTPase-activating protein (GAP) guanine-nucleotide-exchange factor (GEF) Rab GTPase Other examples of Rab cascades will help to establish the links between Rab GTPases of yet unknown function. My laboratory recently identified two...
Articles
Specific localization of Rabs at intracellular membranes
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (6): 1421–1425.
Published: 21 November 2012
... in some cases in order to stimulate GDI dissociation and allow efficient access of the GEF for nucleotide exchange. guanine-nucleotide-dissociation inhibitor (GDI) guanine-nucleotide-dissociation inhibitor displacement factor (GDF) guanine-nucleotide-exchange factor (GEF) Rab Rab membrane...
Articles
The Rab family of proteins: 25 years on
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (6): 1337–1347.
Published: 21 November 2012
... activity [ 30 , 31 ]. disease GTPase-activating protein (GAP) guanine-nucleotide-exchange factor (GEF) G-protein GTPase Rab YPT Thus the question of how Rab proteins are specifically targeted to membranes is still somewhat open and subject to debate. A combination of the various proposed...
Articles
LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (5): 1074–1079.
Published: 19 September 2012
... be addressed (email [email protected] ). 28 3 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 GTPase-activating protein (GAP) guanine-nucleotide-exchange factor (GEF) GTPase kinase leucine-rich repeat kinase 2 (LRRK2) Parkinson's disease ArfGAP1 ADP...
Articles
Signalling over a distance: gradient patterns and phosphorylation waves within single cells
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (5): 1235–1241.
Published: 24 September 2010
... correspondence should be addressed (email [email protected] ). 10 3 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 gradient pattern GTPase-activating protein (GAP) guanine-nucleotide-exchange factor (GEF) phosphorylation wave signalling In the middle...
Articles
Clues to the mechanism of action of eIF2B, the guanine-nucleotide-exchange factor for translation initiation
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (4): 658–664.
Published: 22 July 2008
... hypomyelination (CACH) eukaryotic initiation factor 2B (eIF2B) G-protein guanine-nucleotide-exchange factor (GEF) leukoencephalopathy with vanishing white matter (VWM) translation initiation © The Authors Journal compilation © 2008 Biochemical Society 2008 17 3 2008 1 To whom...