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Keywords: hepatitis C virus
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Articles

SRPK1 inhibition in vivo : modulation of VEGF splicing and potential treatment for multiple diseases

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Sebastian Oltean, Melissa Gammons, Richard Hulse, Maryam Hamdollah-Zadeh, Athina Mavrou, Lucy Donaldson, Andrew H. Salmon, Steve J. Harper, Michael R. Ladomery, David O. Bates
Journal: Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (4): 831–835.
https://doi.org/10.1042/BST20120051
Published: 20 July 2012
... in regulation of many cellular processes. It is therefore crucial to carry out overexpression and inhibition studies in vivo to fully characterize the essential as well as redundant SRPK1 functions in physiology and pathology. age-related macular degeneration diabetic nephropathy hepatitis C virus...
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Articles

Regulation and biological function of the liver-specific miR - 122

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Andrew P. Lewis, Catherine L. Jopling
Journal: Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (6): 1553–1557.
https://doi.org/10.1042/BST0381553
Published: 24 November 2010
... of differentiation. miR - 122 is a highly liver-specific miRNA that is important in hepatitis C virus infection, cholesterol metabolism and hepatocellular carcinoma. In the present review, we discuss the effects of miR - 122 on liver physiology and pathology. Recent evidence of pathways involved in the regulation...
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