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Keywords: histones
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Biochem Soc Trans (2024) 52 (3): 1219–1232.
Published: 23 May 2024
...Devisree Valsakumar; Philipp Voigt Nucleosomes constitute the fundamental building blocks of chromatin. They are comprised of DNA wrapped around a histone octamer formed of two copies each of the four core histones H2A, H2B, H3, and H4. Nucleosomal histones undergo a plethora of posttranslational...
Biochem Soc Trans (2023) 51 (5): 1749–1763.
Published: 18 September 2023
...Kimberly N. Espinoza Pereira; Jixiu Shan; Jonathan D. Licht; Richard L. Bennett Genes encoding histone proteins are recurrently mutated in tumor samples, and these mutations may impact nucleosome stability, histone post-translational modification, or chromatin dynamics. The prevalence of histone...
Biochem Soc Trans (2023) 51 (3): 1035–1046.
Published: 12 May 2023
... information, they can take on similar or different cell fates, resulting from a symmetric or asymmetric division. These fates can be modulated by epigenetic mechanisms that can alter gene expression without changing genetic information. Histone proteins, which wrap DNA into fundamental units of chromatin...
Biochem Soc Trans (2022) 50 (1): 21–32.
Published: 22 February 2022
... neutrophils, macrophages can release extracellular traps following exposure to a range of pathogenic and pro-inflammatory stimuli. Extracellular traps are released by a specialised cell death pathway termed ‘ETosis', and consist of a backbone of DNA and histones decorated with a range of other proteins...
Biochem Soc Trans (2020) 48 (6): 2753–2767.
Published: 10 December 2020
...Natalia Elisa Bernardes; Yuh Min Chook The transport of histones from the cytoplasm to the nucleus of the cell, through the nuclear membrane, is a cellular process that regulates the supply of new histones in the nucleus and is key for DNA replication and transcription. Nuclear import of histones...