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Keywords: induced pluripotent stem cell
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Articles
Biochem Soc Trans (2014) 42 (5): 1270–1274.
Published: 18 September 2014
... induced pluripotent stem cell induced neural progenitor non-neuronal cell Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by death of upper and lower motor neurons, which results in muscle wasting and death from respiratory failure typically within 2–5...
Articles
Biochem Soc Trans (2010) 38 (4): 1033–1036.
Published: 26 July 2010
... alternative sources of human hepatocytes which circumvent these issues. The research in our group has focused on generating human hepatic endoderm from the scalable pluripotent stem cell populations, human embryonic stem cells and induced pluripotent stem cells. We have developed efficient and scalable models...
Articles
Biochem Soc Trans (2010) 38 (4): 1051–1057.
Published: 26 July 2010
... mature forms of many lineages; and (iii) the ability to express genotypes of interest via the selection of donors, whether they be of embryonic origin, through pre-implantation genetic diagnosis, or adults, by genetic reprogramming of somatic cells, so-called iPSCs (induced pluripotent stem cells...
Articles
Biochem Soc Trans (2010) 38 (4): 1046–1050.
Published: 26 July 2010
...Ivana Barbaric; Paul J. Gokhale; Peter W. Andrews Human ES (embryonic stem) cells and iPS (induced pluripotent stem) cells have been heralded as a source of differentiated cells that could be used in the treatment of degenerative diseases, such as Parkinson's disease or diabetes. Despite the great...