... are reviewed and the potential clinical applications of this strategy are discussed. © The Authors Journal compilation © 2014 Biochemical Society 2014 cell replacement cell reprogramming induced pluripotent stem cell (iPSC) pluripotency 1 To whom correspondence should be addressed (email...

... Biochemical Society 2013 autophagy dopaminergic neuron induced pluripotent stem cell (iPSC) leucine-rich repeat kinase 2 (LRRK2) mitochondrion Parkinson’s disease (PD) Disease models may be used to describe phenotypes that ideally represent disease states, and subsequently...

... Biochemical Society 2012 induced pluripotent stem cell (iPSC) leucine-rich repeat kinase 2 (LRRK2) Parkinson's disease reprogramming Although it has been shown that PD fibroblasts can be directly converted into dopaminergic neurons [ 25 ], this work is still in its infancy, and further tests...

... organization Emery–Dreifuss muscular dystrophy (EDMD) Hutchinson–Gilford progeria syndrome (HGPS) induced pluripotent stem cell (iPSC) nuclear envelope disease reactive oxygen species (ROS) The Nuclear Envelope Disease and Chromatin Organization UK was formed in 2005, to unite and promote...

... (email [email protected] ). 11 7 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 aging Hutchinson–Gilford progeria syndrome (HGPS) induced pluripotent stem cell (iPSC) lamin A/C progeria HGPS is a rare congenital disease characterized by accelerated...