... (Integrator), CPA (cleavage & polyadenylation) are indicated. See text for further detail. While CPA is a major player in Pol II transcription termination, it has recently become apparent that other, potentially generic, mechanisms also exist. Here, the Integrator complex is the best described...

... the Integrator complex. Since their initial discovery, Integrator proteins have been implicated not only in the production of snRNA, but also in other cellular processes that may be independent of snRNA biogenesis. In the present study, we discuss snRNA biosynthesis and the roles of Integrator proteins. We...