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Keywords: integrin αIIbβ3
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Biochem Soc Trans (2004) 32 (2): 387–392.
Published: 01 April 2004
... responses involves affinity regulation of the major platelet integrin αIIbβ3, the primary receptor mediating platelet aggregation and thrombus growth. The input signals regulating integrin αIIbβ3 can be divided into three main groups: (1) G q -coupled receptors linked to the activation of PLCβ...