... structures of CTXφ pIII unbound and in complex with Vibrio cholerae TolA reveal novel interaction interfaces J. Biol. Chem. 2012 287 36258 36272 bacteriocin colicin hub protein interactome Tol protein translocation Bacteriocins produced by Gram-negative bacteria are plasmid...

... code, the ‘heparanome’, that confers the ability to interact selectively with a wide interactome of proteins, the ‘heparactome’, and thereby influence a network of cellular events. It is becoming increasingly apparent that understanding the structure–activity relationships of these enigmatic molecules...

...Mike P. Williamson; Michael J. Sutcliffe In the present article, we describe the two standard high-throughput methods for identification of protein complexes: two-hybrid screens and TAP (tandem affinity purification) tagging. These methods have been used to characterize the interactome...

... will be presented to exploit interaction information for the inference of protein structure, function, signalling pathways and ultimately entire interactomes. Interaction networks can be modelled as graphs, showing the operation of gene function in terms of protein interactions. Since the architecture of biological...

... is usually called the interactome. In thisworkwe are concerned onlywith pairwise interactions, butwewill use the term interactome to refer to this restricted set of interactions. The Y2H (yeast two-hybrid) system is a molecular technique for determining whether two proteins, or parts of proteins, interact [1...